ASPET’s Editors-in-Chief each selected an article from their journals, published in 2025, to be marked as free-to-read for the month of December. We invite you to explore and share the following research with your colleagues:
ASPET Discovery: “Evaluation of molecular glue–induced neomorphic protein-protein interaction with a cell lysate–based time-resolved fluorescence resonance energy transfer assay.” This paper unveils innovative approaches for studying protein interactions. ASPET Discovery is fully open access, and all of its articles are free-to-read.
Drug Metabolism and Disposition: “DDI–CYP: Metabolism ensemble models for drug-drug interaction predictions.” This article introduces advanced ensemble modeling approaches for predicting drug-drug interactions involving CYP enzymes, supporting safer and smarter therapeutic decisions.
The Journal of Pharmacology and Experimental Therapeutics: “Evidence for cytoprotective autophagy in response to HER2-targeted monoclonal antibodies.” A study that sheds new light on how autophagy may help cells respond to targeted therapies, offering insights that could shape future cancer treatments.
Molecular Pharmacology: “Simulating early steps in nicotine dependence: Pharmacokinetics, activation, and chaperoning of nicotinic receptors.” This paper unpacks the underlying mechanisms of nicotine addiction, offering valuable perspectives on receptor pharmacology and early dependence processes.
Pharmacological Reviews: “Bioactives from marine resources as natural health products: A review.” A comprehensive review that explores how marine-derived compounds are shaping the future of natural health products and modern pharmacology.
